| 摘要 |
PROBLEM TO BE SOLVED: To provide a membrane by which protein is selectively adsorbed and a purified at a high recovery rate by chemically bonding a side chain having a functional group such as neutral hydroxyl group to the surface of the membrane pore of a porous base material membrane having a three-dimensional network structure and specifying the functional group and physical properties of the membrane. SOLUTION: A side chain having a neutral hydroxyl group of at least 0.1 millimol per 1g porous membrane and a functional group of formula I or II (wherein, R is a 3 or more C alkyl, a phenyl or an alkylated phenol group) of at least 0.05millimol is chemically bonded to the surface of the membrane pore of a porous base material membrane essentially having a three dimensional network structure such as a polyolefin and a copolymer of an olefin and a halogenated olefin. Moreover, the membrane is used which has pressure breaking water of at most 0.1 mega pascal, 0.01-5μm mean pore diameter and 20-90% vacancy rata. Protein is purified at a low operation pressure and at a high treatment speed and recovered by utilizing hydrophobic interaction through the hydrophobic selective absorption porous membrane obtained by such a way.
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