发明名称 SYNTHETIC CALIBRATOR FOR USE IN IMMUNOASSAY CONTAINING BODY UNDER TEST FORMED AS COMPOSITE FOR INACTIVE CARRIER MOLECULEOR PARTIAL ALIGNMENT THEREOF
摘要 PROBLEM TO BE SOLVED: To obtain a stable calibrator capable of being used for calibrating an immunity assay by coupling a specimen specific epitope to other protein or synthetic calibrator. SOLUTION: This formulation contains a chemical coupling part to a complex formable carrier molecule immunologically inactive for specimen or its partial array. This synthetic calibrator substance exists in physiological buffer having particularly salt concentration of 0.05 to 0.5M and particularly pH condition of 6 to 8 of pH. The molecule can be constituted by protein or polymer containing complex formable group. The suitable carrier molecule is preferably macroprotein. The suitable synthetic carrier substance is polymer such as, for example, polyvinyl alcohol, polyacrylate, and the coupling of peptide to the compounds is executed by using corresponding functional group.
申请公布号 JPH0926423(A) 申请公布日期 1997.01.28
申请号 JP19960189921 申请日期 1996.07.02
申请人 BAYER AG 发明人 MARUGITO DOTO;KURISUTOFU PETORI
分类号 G01N33/543;A61K38/00;C07K14/47;C07K17/02;C07K19/00;G01N33/53;G01N33/68;G01N33/96;(IPC1-7):G01N33/543 主分类号 G01N33/543
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