Lactone stable formulation of camptothecin and methods for uses thereof

摘要

Camptothecin (CPT) an anticancer drug is poorly soluble in water. This invention overcomes this limitation by teaching novel pharmaceutically acceptable lactone stable CPT formulations for the direct administration of CPT to human subjects with cancer. The claimed invention also describes novel dosages, schedules, and routes of administration of the lactone stable CPT formulations to patients with various forms of cancer.