发明名称 Process for producing intermediate for 13,14-didehydroprostaglandin E
摘要 PCT No. PCT/JP94/00243 Sec. 371 Date Aug. 10, 1995 Sec. 102(e) Date Aug. 10, 1995 PCT Filed Feb. 17, 1994 PCT Pub. No. WO94/19319 PCT Pub. Date Sep. 1, 1994A novel process for the production of a compound represented by the formula: <IMAGE> wherein Z and Z' each represents a protective group for the hydroxyl group; R1 represents a hydrogen atom or an alkyl group; R2 represents an alkyl group, a cycloalkyl group, an alkenyl group, an alkynyl group, a group represented by the formula -B-D (in which B is an alkylene group and D is a substituted or unsubstituted phenyl group, a substituted or unsubstituted phenoxy group or a cycloalkyl group), a substituted or unsubstituted phenyl group or a substituted or unsubstituted phenoxy group; R3 and R4 each represents a hydrogen atom, an alkyl group or an alkoxy group; R5 represents a hydrogen atom, an alkyl group, an alkoxy group, a halogen atom, a cyano group, an amino group, a hydroxyl group or a group represented by a formula -COOR8; R6 represents a group represented by a formula -COOR9, a cyano group, a hydroxyl group, a group represented by a formula -OCOR10 or a group represented by a formula -CONR11R12; A represents a vinylene group, an ethynylene group, a phenylene group or a group represented by a formula -C=C=C-; X represents an oxygen atom or a sulfur atom; m represents an integer of 0 to 7; n is 0 or 1; each of p and r is an integer of 0 to 5; q is 0 or 1; and s is 0 or 1.
申请公布号 US5597938(A) 申请公布日期 1997.01.28
申请号 US19950505165 申请日期 1995.08.10
申请人 TAISHO PHARMACEUTICAL CO., LTD.;SATO, FUMIE 发明人 SATO, FUMIE
分类号 C07C405/00;(IPC1-7):C07F7/08;C07F7/10;C07F7/18 主分类号 C07C405/00
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