Nucleotide sequences permitting the replication and maintenance of a genetic information in animal cells

摘要

The subject of the invention is the use of a DNA fragment comprising a sequence from the 3' end of the AcNPV baculovirus IE1 gene, optionally combined with a DNA fragment comprising a sequence situated upstream of the promoter of the IE1 gene, for producing vectors permitting the replication and maintenance of genetic information in animal cells. The invention also encompasses the episomal vectors obtained, as well as the transformed cells comprising the vectors.