| 摘要 |
The present invention relates to the new thielocin derivatives, which exhibit phospholipase A2 inhibitory activity of the formula: <IMAGE> wherein R1, R2, R3, R4, R5, R6, R7, and R8 are independently hydrogen, lower alkyl, lower alkoxy, hydroxy, or halogen; E1 and E2 are independently hydrogen, or an ester residue; m and n are independently an integer of 0 to 4; -Y- is a bivalent group which is selected from the group consisiting of the following radicals: CH2CH2, CHCH, <IMAGE> <IMAGE>ts thereof.
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