发明名称 (THIOPHEN-2-YL)-PIPERIDIN OR TETRAHYDROPYRIDIN AZABICYCLOCARBOXAMIDES
摘要 This invention provides compounds having the structure <IMG> wherein R is hydrogen, alkyl, alkenyl, alkynyl, -COR the dotted line represents an optional double bond; R1 is hydrogen, -OH, OR3, or is absent if the optional double bond is present; R phenylalkyl; R4 is hydrogen, -OR5, alkyl, alkenyl, alkynyl, -COR5, -CO2R5, -CONR5R6, perhaloalkyl, halogen, phenyl, or phenylalkyl; R5 and R6 are each, independently, hydrogen, alkyl, alkenyl, alkynyl, phenyl, or phenylalkyl; and n = 0 - 2 or a pharmaceutically acceptable salt thereof that are useful as antipsychotic, antidepressant and anxiolytic agents useful in the treatment and relief of the symptoms of these disease states.
申请公布号 CA2181759(A1) 申请公布日期 1997.01.27
申请号 CA19962181759 申请日期 1996.07.22
申请人 AMERICAN HOME PRODUCTS CORPORATION 发明人 BAUDY, REINHARDT B.;NELSON, JAMES A.;KANZELBERGER, MIRA A.
分类号 A61P25/18;A61K31/435;A61K31/445;A61P25/00;A61P25/20;A61P25/24;A61P25/26;A61P43/00;C07D451/02;(IPC1-7):C07D451/02;A61K31/46 主分类号 A61P25/18
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