发明名称 Agents for removing advanced glycosylation endproducts
摘要 <p>The present invention relates to a method and associated agents for the inhibition and treatment of protein aging in animals by stimulating the bodies of the animals to increase their recognition and affinity for advanced glycosylation end products. Specifically, the method contemplates the administration of certain agents such as advanced glycosylation endproducts, such endproducts as are bound to the carrier, monokines that stimulate phagocytic cells to increase their activity toward advanced glycosylation endproducts, and mixtures of these materials either alone, or in conjunction with other co-stimulatory agents. Numerous diagnostic and therapeutic applications are defined, and pharmaceutical compositions are also contemplated.</p>
申请公布号 EP0259893(B1) 申请公布日期 1997.01.22
申请号 EP19870113386 申请日期 1987.09.14
申请人 THE ROCKEFELLER UNIVERSITY 发明人 VLASSARA, HELEN;BROWNLEE, MICHAEL;CERAMI, ANTHONY
分类号 C12N5/06;A61K31/4178;A61K35/12;A61K38/00;A61K38/19;A61K38/20;A61K38/21;A61K38/38;A61K39/00;A61K45/00;A61K51/00;A61P3/00;A61P39/02;A61P43/00;C07K16/28;G01N33/50;G01N33/53;G01N33/531;G01N33/573;G01N33/66;G01N33/68;(IPC1-7):A61K45/06;G01N33/48 主分类号 C12N5/06
代理机构 代理人
主权项
地址