摘要 |
PURPOSE:To readily and stably for long time obtain the subject compound in high reactivity and selectivity by reducing acetone with hydrogen using carried ruthenium catalyst and reacting so as concentration of isopropyl alcohol of reaction element to be specific value. CONSTITUTION:Acetone is supplied H2 in an amount of 1 to 50 times of theoretically required hydrogen to a reducing reaction by hydrogen preferably using isopropyl alcohol(IPA) as a solvent, where the concentration of IPA in the reaction system is made as >=50wt.%, then reacted at 0 to 200 deg.C under normal pressure or increased pressure in the presence of ruthenium catalyst such as ruthenium chloride carrying 0.01 to 5wt.% carrier such as heat-resistance gamma-alumina, silica or activated charcoal of coconut shell to afford the objective compound useful as solvent or raw materials of various organic drugs, etc. |