发明名称 |
IMPROVED PROCESS FOR SYNTHESIZING CARBAPENEM INTERMEDIATES |
摘要 |
A process of synthesizing a compound of formula (1) or (2) is disclosed wherein R represents H or methyl and P represents triethylsilyl or trimethylsilyl. A compound of formula (3) or (4) is reacted with P-C1 wherein P is as defined above, in the presence of base and a substantially nonreactive solvent to produce (1) or (2).
|
申请公布号 |
CA2224439(A1) |
申请公布日期 |
1997.01.16 |
申请号 |
CA19962224439 |
申请日期 |
1996.06.24 |
申请人 |
MERCK & CO., INC. |
发明人 |
YASUDA, NOBUYOSHI;YANG, CHUNHUA |
分类号 |
C07D205/08;C07D477/02;C07F7/18;(IPC1-7):C07F7/10 |
主分类号 |
C07D205/08 |
代理机构 |
|
代理人 |
|
主权项 |
|
地址 |
|