发明名称 |
TISSUE SPECIFIC VIRAL VECTORS |
摘要 |
Host cell specific adenovirus vehicles are provided for transfecting target host cells. By providing for transcriptional initiating regulation dependent upon transcription factors that are only active in specific, limited cell types, virus replication will be restricted to the target cells. The modified adenovirus may be used as a vehicle for introducing new genetic capability, particularly associated with cytotoxicity for treating neoplasia.
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申请公布号 |
WO9701358(A1) |
申请公布日期 |
1997.01.16 |
申请号 |
WO1996US10838 |
申请日期 |
1996.06.26 |
申请人 |
CALYDON |
发明人 |
HENDERSON, DANIEL, ROBERT;SCHUUR, ERIC, RODOLPH |
分类号 |
C12N15/09;A61K35/76;A61K48/00;C12N7/00;C12N9/64;C12N15/00;C12N15/861;C12R1/92;(IPC1-7):A61K48/00 |
主分类号 |
C12N15/09 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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