发明名称 |
Assessment of allelic variation in vitamin D receptor correlated to bone density or turnover |
摘要 |
PCT No. PCT/AU93/00394 Sec. 371 Date Mar. 2, 1995 Sec. 102(e) Date Mar. 2, 1995 PCT Filed Aug. 2, 1993 PCT Pub. No. WO94/03633 PCT Pub. Date Feb. 17, 1994The present invention provides a genetic test for assaying predisposition to and/or resistance to high rates of bone turnover, development of low bone mass and responsiveness or otherwise to therapeutic modalities. This is a specific model for use in prediction of osteoporosis and likely response to preventive or therapeutic modalities. It is a general model of allelic variation in transcriptional regulators determining physiological set-points and thus susceptibility or resistance to certain pathophysiological states.
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申请公布号 |
US5593833(A) |
申请公布日期 |
1997.01.14 |
申请号 |
US19950379496 |
申请日期 |
1995.03.02 |
申请人 |
GARVAN INSTITUTE OF MEDICAL RESEARCH |
发明人 |
MORRISON, NIGEL A.;EISMAN, JOHN A.;KELLY, PAUL J. |
分类号 |
C12N15/09;A61K38/00;C07H21/04;C07K14/705;C12Q1/68;(IPC1-7):C12Q1/68;C12P19/34;C07H21/02 |
主分类号 |
C12N15/09 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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