| 摘要 |
PROBLEM TO BE SOLVED: To form chemically distinguished pictures under a scanning atomic power microscope by using a chemically denatured probe which forms pictures in a vertical force mode, an elastic mode, a tapping mode, and non-contact mode. SOLUTION: The tip 4 of a probe is coated with a vapor-deposited metallic coating layer 6 and a thiocarboxylic acid layer 7 which is formed by absorption from a liquid phase by utilizing a thiol radical having affinity with the gold of the layer 6. Consequently, a stable 'acidic tip' for detecting basic group and hydrogen bridge is formed. An assay sample 5 is set below the acidic tip. The sample 5 is first coated with butyl trimethoxysilane having a methyl end group, and then, the uncoated part of the sample 5 is coated with buthyl trimethoxysilance having an amino end group by dipping the sample 5 in the solution of the buthyl trimethoxysilane. Therefore, a chessboard-like pattern is formed of the silane monomolecular layers having the methyl and amino end groups. |
