| 发明名称 |
DERIVATIVES OF N-(HYDROXYETHYL)-BUTANEDIAMIDE OR THEIR ACID-ADDITIVE SALTS AND PHARMACEUTICAL COMPOSITION SHOWING PROPERTY OF RENNIN INHIBITOR |
| 摘要 |
FIELD: organic chemistry. SUBSTANCE: product: derivatives of N-(hydroxyehyl)-butanediamide of the general formula A-N(R)C(O)CHCH(R)C(O)-B where substituents A, R,Rand B have values indicated in point 1 of invention, or their acid-additive salts that can be used as an active substance in pharmaceutical composition showing property of rennin inhibitor. EFFECT: improved method of synthesis, enhanced effectiveness. |
| 申请公布号 |
RU95113446(A) |
申请公布日期 |
1997.01.10 |
| 申请号 |
RU19950113446 |
申请日期 |
1995.04.24 |
| 申请人 |
BIO-MEGA/BERINGER INGEL'KHEJM RISERCH INK. |
发明人 |
POL' KEJTS ANDERSON;TEDDI KHAL'MOS;GREJS LORENA JANG;MARK-ANDRE PUPAR;BRJUNO SIMONO |
| 分类号 |
A61K31/16;A61K31/165;A61K31/40;A61K31/4015;A61K31/415;A61K31/42;A61K31/44;A61K31/4402;A61K31/4406;A61K31/4418;A61P9/12;A61P43/00;C07C233/18;C07C233/19;C07C237/22;C07D207/26;C07D207/27;C07D213/40;C07D233/54;C07D233/64;C07D277/28;C07D277/30;C07D277/40;C07D317/58;C07D417/12 |
主分类号 |
A61K31/16 |
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