摘要 |
Nucleic acid molecules encoding human neuronal nicotinic acetylcholine receptor alpha and beta subunits, mammalian and amphibian cells containing the nucleic acid molecules, and methods for producing alpha and beta subunits are provided. In particular, nucleic acid molecules encoding alpha 6 subunits and molecules encoding beta 3 subunits of human neuronal nicotinic acetylcholine receptors are provided. In addition, combinations of a plurality of subunits, such as one or more of alpha 1, alpha 2, alpha 3, alpha 4, alpha 5, alpha 6, and/or alpha 7 subunits in combination with one or more of beta 3 subunits or such as one or more of beta 2, beta 3 and/or beta 4 subunits in combination with an alpha 6 subunit are provided. |