RECEPTOR:RELEASE LIGAND (RELAND) COMPLEXES AND ASSAYS AND KITS BASED THEREON

摘要

Receptor:release ligand complexes and kits based thereon are used in a method for assaying for the presence of analyte in a sample, by detecting a released component of the complex -- receptor or ligand. The complexes are stable in the absence of analyte, but unstable when contacted with the analyte, leading to release of the ligand. The term "release ligand" or "reland" is applied to such a ligand. Either the released ligand or released receptor is detected by means of a detection system carried by either. The receptor:ligand complex may be formed in situ or may be pre-formed.