发明名称 SILICON-BASED SLEEVE DEVICES FOR CHEMICAL REACTIONS
摘要 A silicon-based sleeve type chemical reaction chamber (41) that combines heaters, such as doped polysilicon for heating, and bulk silicon for convection cooling. The reaction chamber combines a critical ratio of silicon and silicon nitride to the volume of material to be heated (e.g., a liquid) in order to provide uniform heating, yet low power requirements. The reaction chamber will also allow the introduction of a secondary tube (45) (e.g., plastic) into the reaction sleeve that contains the reaction mixture thereby alleviating any potential materials incompatibility issues. The reaction chamber may be utilized in any chemical reaction system for synthesis or processing of organic, inorganic, or biochemical reactions, such as the polymerase chain reaction (PCR) and/or other DNA reactions, such as the ligase chain reaction, which are examples of a synthetic, thermal-cycling-based reaction. The reaction chamber may be used in synthesis instruments, particularly those for DNA amplification and synthesis.
申请公布号 WO9700726(A1) 申请公布日期 1997.01.09
申请号 WO1996US10453 申请日期 1996.06.17
申请人 THE REGENTS OF THE UNIVERSITY OF CALIFORNIA 发明人 NORTHRUP, M., ALLEN;MARIELLA, RAYMOND, P.;CARRANO, ANTHONY, V.;BALCH, JOSEPH, W.
分类号 C12N15/09;B01J19/00;B01L7/00;B81B1/00;B81C3/00;C12M1/00;C12Q1/68;G01N21/03;G01N21/05;G01N21/69;G01N21/76;(IPC1-7):B01L3/00 主分类号 C12N15/09
代理机构 代理人
主权项
地址