| 发明名称 |
PROGESTERONE ANALOGS TO REVERSE MULTIDRUG RESISTANCE |
| 摘要 |
The present invention is directed to novel progesterone derivatives, as well as to pharmaceutical compositions thereof, and methods of treatment using the derivatives. More particularly, the invention relates to C7-substituted derivatives of the pregnene series. The present invention is directed to methods of treating multidrug-resistant tumors, and especially breast tumors, with novel C7-substituted progesterone analogs.
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| 申请公布号 |
WO9700683(A1) |
申请公布日期 |
1997.01.09 |
| 申请号 |
WO1996US10751 |
申请日期 |
1996.06.24 |
| 申请人 |
GEORGETOWN UNIVERSITY |
发明人 |
CLARKE, ROBERT;TALEBIAN, ABDEL, H. +DI;GHIORGHIS, ALEM;LEONESSA, FABIO;HAMMER, CHARLES |
| 分类号 |
C07J41/00;(IPC1-7):A61K31/57;A61K31/575;C07J5/00;C07J7/00;C07J9/00;C07J31/00 |
主分类号 |
C07J41/00 |
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