Antigenic group b streptococcus type ii and type iii polysaccharide- fragments having a 2,5-anhydro-d-mannose terminal structure and conjugate vaccine thereof

摘要

The process for depolymerizing Group B Types II and III Streptococcal Polysaccharide is disclosed which results in polysaccharide fragments having a reducing end suitable for conjugating to protein. Conjugate molecules, vaccines and their use to immunize mammals including humans are also disclosed.