The present invention relates to a novel and economical process for the synthesis of HPMP-substituted nucleotide antiviral compounds. Also disclosed are novel intermediates produced in the process for the preparation of HPMPC.
申请公布号
US5591852(A)
申请公布日期
1997.01.07
申请号
US19950482036
申请日期
1995.06.07
申请人
INSTITUTE OF ORGANIC CHEMISTRY AND BIOCHEMISTRY OF THE ACADEMY OF SCIENCES OF THE CZECH REPUBLIC;REGA STICHTING V.Z.W.
发明人
VEMISHETTI, PURUSHOTHAM;BRODFUEHRER, PAUL R.;HOWELL, HENRY G.;SAPINO, JR., CHESTER