发明名称 |
Calanolide and related antiretroviral compounds, compositions, and uses thereof |
摘要 |
The present invention provides novel antiviral compounds, refered to as calanolides, related compounds, and their derivatives, which may be isolated from plants, or derived from compounds from plants, of the genus Calophyllum in accordance with the present inventive method. The compounds and their derivatives may be used alone or in combination with other antiviral agents in compositions, such as pharmaceutical compositions, to inhibit the growth or replication of a virus, such as a retrovirus, in particular a human immunodeficiency virus, specifically HIV-1 or HIV-2.
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申请公布号 |
US5591770(A) |
申请公布日期 |
1997.01.07 |
申请号 |
US19930065618 |
申请日期 |
1993.05.21 |
申请人 |
THE UNITED STATES OF AMERICA AS REPRESENTED BY THE DEPARTMENT OF HEALTH AND HUMAN SERVICES;THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS |
发明人 |
BOYD, MICHAEL R.;CARDELLINA, II, JOHN H.;GUSTAFSON, KIRK R.;MCMAHON, JAMES B.;FULLER, RICHARD W.;CRAGG, GORDON M.;KASHMAN, YOEL;SOEJARTO, DOEL |
分类号 |
A61K31/365;A61K31/366;A61K36/18;A61K45/06;A61P31/12;A61P31/18;C07D493/14;C07D493/22;(IPC1-7):A61K31/365;A61K31/37 |
主分类号 |
A61K31/365 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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