发明名称 |
Crystallization of alpha-L-aspartyl-l-phenylalanine methyl ester from aqueous solution |
摘要 |
Improved method for crystallization of alpha -L-aspartyl-L-phenylalanine methyl ester (aspartame) from an aqueous solution by conductive cooling while avoiding turbulence in the crystallizing system wherein crystallization is carried out with cooling to a temperature level not lower than 10 DEG C in the presence of at least 0.1% by weight of a C3-8 ketone, the amount of ketone and the temperature level being chosen for each individual ketone so that a homogeneous solvent system is present at the start of crystallization and an open drainable network of aspartame crystals is obtained. |
申请公布号 |
EP0751146(A1) |
申请公布日期 |
1997.01.02 |
申请号 |
EP19950201794 |
申请日期 |
1995.06.30 |
申请人 |
HOLLAND SWEETENER COMPANY V.O.F. |
发明人 |
RIJKERS, MARINUS PETRUS WILHELMUS MARIA;VRINZEN, ALEXANDER PETER MARIE |
分类号 |
A23L27/30;C07K5/072;C07K5/075 |
主分类号 |
A23L27/30 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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