发明名称 |
Production of bacteria and yeast of hemoglobin and analogues thereof |
摘要 |
<p>A method of producing a hemoglobin-like protein wherein an alpha globin-like polypeptide and a beta globin-like polypeptide are each expressed in transformed non-erythrocyte cells such as bacterial or yeast cells, the method comprising expressing the alpha and beta globin-like polypeptide in the same cell in such manner that the alpha and beta globin-like polypeptides are assembled and combined with heme so as to intracellularly produce a biologically functional hemoglobin-like protein in soluble, recoverable form. <IMAGE></p> |
申请公布号 |
GR3021106(T3) |
申请公布日期 |
1996.12.31 |
申请号 |
GR19960402467T |
申请日期 |
1996.09.19 |
申请人 |
SOMATOGEN INC.;MEDICAL RESEARCH COUNCIL |
发明人 |
HOFFMAN, STEPHEN J.;LOOKER, DOUGLAS L.;ROSENDAL, MARY S.;STETLER, GARY L.;WAGENBACH, MICHAEL;NAGAI, KIYOSHI |
分类号 |
C07K19/00;A61K38/00;A61K47/48;C07K14/00;C07K14/805;C12N15/09;C12N15/12;C12N15/81;C12P21/02;C12R1/19;C12R1/865;G01N33/53;(IPC1-7):C12N15/12;C07K1/00;G01N33/72 |
主分类号 |
C07K19/00 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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