Azido-substituted fatty acid analog enzyme substrates

摘要

Azido-substituted fatty acid analogs which are useful in the fatty acid acylation of peptides and proteins and as antiviral agents are disclosed having the following chemical structure: Z - (CH2)xCOOR wherein Z = azido, tetrazolyl or triazolyl R = H or C1-C8 alkyl, and x = 8-12 or structure (I) as defined above and wherein a methylene group from carbon position 3 to within 2 carbons of Z is replaced with oxygen or sulfur.