摘要 |
Peptides represented by the following general formula (1) or pharmaceutically acceptable salts thereof, and a bronchodilator or a blood flow ameliorant containing the same as the active ingredient: H-His-Ser-Asp-A-B-Phe-Thr-Asp-C-Tyr-D-Arg-E-Arg-F-Gln-G-Ala-Val-I-J-Tyr-Leu-K-L-M-Leu-N, wherein A represents Ala or Gly; B represents Ile or Val; C represents Asn or Ser; D represents Thr or Ser; E represents Leu or Tyr; F, I and J represent each Lys or Arg, provided that at least one of F, I and J is Arg; G represents Met, Leu or Nle; K represents Asn or Ala; L represents Ser or Ala; M represents Ile or Val; and N represents -NH2 or Asn-NH2, excluding the case where A is Ala, B is Val, C is Asn, D is Thr, E is Leu, K is Asn, L is Ser, M is Ile and N is Asn-NH2 at the same time.
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