摘要 |
This invention relates to new benzamide derivatives having a vasopressin antagonistic activity, etc., and represented by general formula (I), wherein R<1> is aryl optionally substituted with lower alkoxy, etc., R<2> is lower alkyl, etc., R<3> is hydrogen, etc., R<4> is lower alkoxy, etc., R<5> is hydrogen, etc., A is NH, etc., E is (a), etc., X is -CH=CH-, -CH=N-, or S, and Y is CH or N, and pharmaceutically acceptable salts thereof, to processes for preparation thereof and to a pharmaceutical composition comprising the same.
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申请人 |
FUJISAWA PHARMACEUTICAL CO., LTD.;SETOI, HIROYUKI;OHKAWA, TAKEHIKO;ZENKOH, TATSUYA;SAWADA, HITOSHI;SATO, KENTARO;TANAKA, HIROKAZU |
发明人 |
SETOI, HIROYUKI;OHKAWA, TAKEHIKO;ZENKOH, TATSUYA;SAWADA, HITOSHI;SATO, KENTARO;TANAKA, HIROKAZU |