Process for identifying RAR receptor antagonists

摘要

Identification of RAR (Retinoic Acid Receptor) antagonists is effected by: (i) applying to an area of skin, an RAR receptor agonist; (ii) giving systemically or dermally before, during, or after (i), an RAR antagonist; and (iii) measuring the response on the treated part of the skin and comparing to the response obtained when the area is treated as in stage (i) alone.