G-protein receptor hibeb69

摘要

Human G-protein thrombin-like receptor polypeptides and DNA (RNA) encoding such polypeptides and a procedure for producing such polypeptides by recombinant techniques is disclosed. Also disclosed are methods for utilizing such polypeptides for identifying antagonists and agonists to such polypeptides and methods of using the agonists and antagonists therapeutically. Also disclosed are diagnostic methods for detecting a mutation in the G-protein thrombin-like receptor nucleic acid sequences and detecting a level of the soluble form of the receptors in a sample derived from a host.