发明名称 |
Drug mitochondrial targeting agents |
摘要 |
The invention relates to novel targeting drug agents that are targeted for entry into the mitochondria. More specifically, the agents are cisplatin derivatives called mitoplatins which are useful as anti-tumor agents. Mitoplatins are named for their targeting to the mitochondrial DNA via the carnitine-acylcarnitine translocase system. The invention also relates to methods of synthesizing mitoplatins, compositions of matter containing mitoplatins and methods of using the mitoplatins. |
申请公布号 |
AU6385396(A) |
申请公布日期 |
1996.12.24 |
申请号 |
AU19960063853 |
申请日期 |
1996.06.06 |
申请人 |
TRUSTEES OF BOSTON UNIVERSITY |
发明人 |
KOSTA STELIOU |
分类号 |
A61K47/48;C07F1/10;C07F1/12;C07F3/00;C07F15/00 |
主分类号 |
A61K47/48 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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