发明名称 |
T cell growth factor |
摘要 |
The present invention relates generally to a T cell growth factor. More particularly, the present invention relates to a T cell growth factor which comprises a glycoprotein which supports interleukin 2- and interleukin 4-independent growth of helper T cells especially from murine and human sources and further which is capable of augmenting proliferation of IL3- or IL4-responsive cells. Even more particularly, the present invention relates to the helper T cell growth factor P40, pharmaceutical compositions thereof, antibodies thereto and recombinant DNA clones thereof. The present invention also contemplates a method for inducing the proliferation of helper T cells as well as IL3- and Il4-responsive cells. The helper T cells growth factor contemplated herein is useful in the stimulation of specific cells in the immune system, either alone or in combination with IL3 or IL4.
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申请公布号 |
US5587302(A) |
申请公布日期 |
1996.12.24 |
申请号 |
US19900462158 |
申请日期 |
1990.01.08 |
申请人 |
LUDWIG INSTITUTE FOR CANCER RESEARCH |
发明人 |
VAN SNICK, JACQUES;UYTTENHOVE, CATHERINE;SIMPSON, RICHARD J. |
分类号 |
A61K38/00;A61P43/00;C07K14/54;C07K16/24;C12N5/10;C12N15/09;C12P21/02;C12R1/91;(IPC1-7):C12N15/12;C12N15/63 |
主分类号 |
A61K38/00 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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