| 发明名称 |
CONVERSION OF COMPACTIN TO PRAVASTATIN BY ACTINOMADURA |
| 摘要 |
A method for converting compactin to pravastatin is described. Compactin is provided and contacted with an agent derived from Actinomadura under conditions in which the agent converts compactin to pravastatin. Also described are an Actinomadura strain, an Actinomadura cell free extract, an Actinomadura hydroxylase, and a method for lowering cholesterol levels in mammals. |
| 申请公布号 |
CA2223122(A1) |
申请公布日期 |
1996.12.19 |
| 申请号 |
CA19962223122 |
申请日期 |
1996.06.04 |
| 申请人 |
MASSACHUSETTS INSTITUTE OF TECHNOLOGY |
发明人 |
DEMAIN, ARNOLD L.;YASHPHE, JACOB;PENG, YULIN;DAVIS, JOSEPH |
| 分类号 |
A61K31/22;A61P3/06;C07D309/30;C12N1/20;C12N9/02;C12P7/62;C12P17/06;C12R1/01;C12R1/03;C12R1/645 |
主分类号 |
A61K31/22 |
| 代理机构 |
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