发明名称 |
AN IMPROVED PEPTIDE, IMMUNOGENIC COMPOSITION AND VACCINE OR MEDICAL PREPARATION, A METHOD TO IMMUNISE ANIMALS AGAINST THE HORMONE LHRH, AND ANALOGS OF THE LHRH TANDEM REPEAT PEPTIDE AND THEIR USE AS VACCINE |
摘要 |
The invention relates to a modified tandem LHRH-peptide vaccine preparation in which the amino acid glycine at position (6) of one or both LHRH decapeptides that constitute the tandem unit is substituted by a dextrorotatory amino acid that contains a side chain to which a carrier compound can be coupled. In addition, the tandem LHRH-peptide can be brought into a tandem-dimer form which is also suitable for producing a vaccine that is effective against LHRH (luteinizing hormone releasing hormone) also referred to as GnRH (gonadotropin-releasing hormone), for immunological castration, to inhibit or affect reproductive functions or to affect behaviour in vertebrates in general and in domesticated animals and man in particular.
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申请公布号 |
WO9640755(A1) |
申请公布日期 |
1996.12.19 |
申请号 |
WO1996NL00223 |
申请日期 |
1996.06.06 |
申请人 |
DLO INSTITUUT VOOR DIERHOUDERIJ EN DIERGEZONDHEID;MELOEN, ROBERT, HANS;OONK, HENDRICA, BERENDINA |
发明人 |
MELOEN, ROBERT, HANS;OONK, HENDRICA, BERENDINA |
分类号 |
A01K67/00;A61K39/00;A61K39/385;A61K39/39;A61P15/00;C07K7/23;(IPC1-7):C07K7/23 |
主分类号 |
A01K67/00 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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