BINDING DOMAINS FROM PLASMODIUM VIVAX AND PLASMODIUM FALCIPARUM ERYTHROCYTE BINDING PROTEINS
摘要
The present invention provides isolated polypeptides useful in the treatment and prevention of malaria caused by Plasmodium falciparum or P. vivax. In particular, the polypeptides are derived from the binding domains of the proteins in the DBL family as well as the sialic acid binding protein (SABP) on P. falciparum merozoites. The polypeptides may also be derived from the Duffy antigen binding protein (DABP) on P. vivax merozoites.
申请公布号
WO9640766(A2)
申请公布日期
1996.12.19
申请号
WO1996US09508
申请日期
1996.06.07
申请人
THE GOVERNMENT OF THE UNITED STATES OF AMERICA, RE
发明人
SIM, KIM, LEE;CHITNIS, CHETAN;MILLER, LOUIS, H.;PETERSON, DAVID, S.;SU, XIN-ZHUAN;WELLEMS, THOMAS, E.