摘要 |
<p>The present invention relates to modified hemoglobin-like compounds. The novel compounds include a globin-like polypeptide containig at least two dialpha domains and multimeric hemoglobin-like proteins having a core hemoglobin-like moeity directly attached to at least two other hemoglobin-like moieties. The invention also relates to nucleic acid molecules encoding the novel polypeptides. Methods of making and purifying the multimeric hemoglobin-like proteins are also provided, as well as compositions containing the proteins.</p> |