发明名称 |
MONOSPECIFIC ANTIBODIES AGAINST A SUBUNIT OF FIBRINOGEN |
摘要 |
The invention provides monospecific antibodies which are specifically reactive with the alpha E subunit of fibrinogen or a fragment thereof, but not with other portions of the fibrinogen molecule. The invention also provides anti- alpha E probes, including monospecific anti- alpha E antibodies which have been detectably labeled. In addition, the invention provides methods for using the monospecific antibodies for detection of the alpha E subunit and fragments thereof, as well as reagents and kits performing the methods. Diagnostic methods for determining information associated with atherogenesis and/or thrombogenesis, as well as for determining information associated with pregnancy status or outcome. The invention further provides continuous cell lines which produce monospecific anti- alpha E antibodies.
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申请公布号 |
WO9641170(A1) |
申请公布日期 |
1996.12.19 |
申请号 |
WO1996US09399 |
申请日期 |
1996.06.07 |
申请人 |
THE NEW YORK BLOOD CENTER, INC. |
发明人 |
GRIENINGER, GERD;FU, YIPING;CAO, YAN;AHADI, MOHAMAD, ZAHER;KUDRYK, BOHDAN, J. |
分类号 |
C12N15/02;C07K16/18;C07K16/36;C12N5/10;C12P21/08;G01N33/50;G01N33/53;G01N33/577;(IPC1-7):G01N33/53;G01N33/542 |
主分类号 |
C12N15/02 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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