| 发明名称 |
Dihydropyridine NPY antagonists: piperazine derivatives |
| 摘要 |
A series of non-peptidergic antagonists of NPY have been synthesized and are comprised of piperazine and homopiperazine derivatives of 4-phenyl-1,4-dihydropyridines of Formula (I). <CHEM> As antagonists of NPY-induced feeding behavior, these compounds are expected to act as effective anorexiant agents in promoting weight loss and treating eating disorders. |
| 申请公布号 |
AU5475696(A) |
申请公布日期 |
1996.12.19 |
| 申请号 |
AU19960054756 |
申请日期 |
1996.06.06 |
| 申请人 |
BRISTOL-MYERS SQUIBB COMPANY |
发明人 |
GRAHAM S. POINDEXTER;MARC BRUCE;GRAHAM JOHNSON;MICHAEL KOZLOWSKI;KAREN LEBOULLUEC;IVO MONKOVIC;RAMAKRISHNA SEETHALA;CHARLES P. SLOAN |
| 分类号 |
A61K31/4427;A61K31/445;A61K31/451;A61K31/455;A61K31/495;A61K31/55;A61P3/04;A61P9/12;A61P25/20;A61P25/24;A61P25/26;A61P43/00;C07D211/90;C07D401/12;C07D413/04;C07D413/14 |
主分类号 |
A61K31/4427 |
| 代理机构 |
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