D-amino acid histatins and histatin-based peptides and methods for treatment of fungal or bacterial infection are described. These D-amino acid histatins and histatin-based peptides are longer-acting anti-fungal or anti-bacterial agents than their L-enantiomeric analogues.
申请公布号
WO9640770(A2)
申请公布日期
1996.12.19
申请号
WO1996US09962
申请日期
1996.06.07
申请人
PERIODONTIX, INC.;TRUSTEES OF BOSTON UNIVERSITY;OPPENHEIM, FRANK, G.;XU, TAO;SPACCIAPOLI, PETER;ROBERTS, F., DONALD;FRIDEN, PHILLIP, M.
发明人
OPPENHEIM, FRANK, G.;XU, TAO;SPACCIAPOLI, PETER;ROBERTS, F., DONALD;FRIDEN, PHILLIP, M.