发明名称 |
MALE INFERTILITY Y-DELETION DETECTION WITH MULTIPLEX PRIMER COMBINATIONS |
摘要 |
The present disclosure describes a method for probing the integrity of a Y chromosome utilizing multiplex PCR reactions which amplify specific regions of the human Y chromosome which have been linked to normal fertility in human males. The method is capable of detecting deletion mutations within the Y chromosome which are predictive of human male infertility. A kit containing reagents needed to practice the method is also disclosed.
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申请公布号 |
WO9641007(A1) |
申请公布日期 |
1996.12.19 |
申请号 |
WO1996US09421 |
申请日期 |
1996.06.06 |
申请人 |
PROMEGA CORPORATION |
发明人 |
FIRST, MARIJO, K.;AGOULNIK, ALEXANDER, I.;MUALLEM, ARIEGE |
分类号 |
C12N15/09;C12Q1/68;(IPC1-7):C12Q1/68 |
主分类号 |
C12N15/09 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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