ISOSPORA SUIS VACCINE

摘要

Isospora suis is propagated using a swine testicular cell line which facilitates production of sporozoites and merozoites, either or both of which can be used in a vaccine for swine. Neutralizing antibodies against sporozoites have been made, and DNA encoding a portion of an apparent sporozoite attachment protein or a derivative or mutant thereof may likewise be used in a vaccine. Nursing piglets can be passively protected from infection by Isospora suis by inoculating the dam and permitting the piglets to nurse from the dam.