NON-BIOLOGICAL PATCH FOR HEMOSTASIS

摘要

A hemostatic patch that is advantageously safe and inexpensive is created that comprises a sponge, and an effective amount of epsilon aminocaproic acid and a thrombin receptor activating peptide for promoting hemostasis. Epsilon aminocaproic acid is a hemostatic agent that inhibits fibrinolysis, accelerates the activity of thrombin and possesses antibacterial properties. Thrombin receptor activating peptide activates platelets and promotes platelet aggregation. The patch is particularly effective for decreasing bleeding of parenchymal organs, as well as for topical use particularly in a bandage form. The bandage form comprises a backing member (10) located contiguous with an exterior surface of the patch (20) and opposite the wound contacting surface of the patch (30). A flap (15) extends from the backing member (10) and a medically acceptable adhesive (25) can be applied onto the flap.