发明名称 |
THE REGULATION OF SYSTEMIC IMMUNE RESPONSES UTILIZING CYTOKINES AND ANTIGENS |
摘要 |
<p>A method of altering the specific, systemic immune response of an individual to a target antigen by the co-administration of a cytokine, an adhesion or accessory molecule, and the target antigen. The target antigen may be a tumor cell, a tumor cell antigen, an infectious agent or other foreign antigen, or other antigens to which an enhanced systemic immune response is desirable. Alternatively, the antigen may be a non-foreign antigen when a suppression of a systemic immune response is desired. The resulting systemic immune response is specific for the target antigen.</p> |
申请公布号 |
WO9640267(A1) |
申请公布日期 |
1996.12.19 |
申请号 |
WO1996US08422 |
申请日期 |
1996.06.03 |
申请人 |
WHITEHEAD INSTITUTE FOR BIOMEDICAL RESEARCH;JOHNS HOPKINS UNIVERSITY SCHOOL OF MEDICINE |
发明人 |
DRANOFF, GLENN;MULLIGAN, RICHARD, C.;PARDOLL, DREW |
分类号 |
C12N15/09;A61K38/00;A61K39/00;A61K39/21;A61K39/39;A61K48/00;A61P35/00;A61P37/02;A61P43/00;C07K14/52;C07K14/525;C07K14/535;C07K14/54;C07K14/545;C07K14/55;C07K14/57;C07K14/705;C12N5/10;C12N15/85;(IPC1-7):A61K48/00 |
主分类号 |
C12N15/09 |
代理机构 |
|
代理人 |
|
主权项 |
|
地址 |
|