发明名称 PROCEDIMIENTO PARA LA SEPARACION DE PRODUCTOS DE DESINTE- GRACION DE DELTA4,20,22-BUFATRIENOLIDOS.
摘要 <p>Decomposition products of DELTA4,20,22- bufatrienolides and process for their separation. Acid hydrolysis of proscillaridine (I) results in mixtures which may contain unreacted (I), scillaridine (II) and the following bufatrienolides not hitherto described in literature and forming the subject of this invention. 3alpha, 14beta-di-OH-DELTA4,20,22-bufatrienolide 3alpha, 14beta-diOH-19-oxo-DELTA4,20,22-bufatrienolide 3alpha, 14beta, 19-tri-OH-DELTA4,20,22-bufatrienolide 5beta, 14beta-diOH-DELTA3,20,22-bufatrienolide 5beta, 14beta-di-OH-19-oxo-DELTA3,20,22-bufatrienolide 5beta, 14beta, 19-tri-OH-DELTA3,20,22-bufatrienolide 19 hydroxyscillaridine. All these products and the means of separation are claimed. Treatment of cardiac insufficiency.</p>
申请公布号 ES358358(A1) 申请公布日期 1970.06.16
申请号 ES19580003583 申请日期 1968.09.20
申请人 KNOLL, A. G. CHEMISCHE FABRIKEN 发明人
分类号 A61K;(IPC1-7):61K/ 主分类号 A61K
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