This invention relates to the epitopes to which monoclonal antibody 88BV59 and antibody 16.88 react. These antibodies were produced by B-cell lines derived from B-cells of cancer patients actively immunized with autologus tumor antigens. Both epitopes are found on the same antigen in tumor tissue. These epitopes can be used in both diagnostic procedures and therapy for human cancers.
申请公布号
WO9640227(A1)
申请公布日期
1996.12.19
申请号
WO1996US09004
申请日期
1996.06.06
申请人
AKZO NOBEL N.V.;BUTLER, SANDRA, M.;POMATO, NICHOLAS;BOS, EBO;HANNA, MICHAEL, G., JR.;HASPEL, MARTIN, V.;HOOVER, HERBERT, C., JR.
