This invention discloses high-affinity oligonucleotide ligands to lectins, specifically nucleic acid ligands having the ability to bind to the lectins, wheat germ agglutinin, L-selectin, E-selectin and P-selectin. Also disclosed are the methods for obtaining such ligands.
申请公布号
WO9640703(A1)
申请公布日期
1996.12.19
申请号
WO1996US09455
申请日期
1996.06.05
申请人
NEXSTAR PHARMACEUTICALS, INC.;PARMA, DAVID, H.;HICKE, BRIAN;BRIDONNEAU, PHILIPPE;GOLD, LARRY
发明人
PARMA, DAVID, H.;HICKE, BRIAN;BRIDONNEAU, PHILIPPE;GOLD, LARRY