| 发明名称 |
SMALL MOLECULE INHIBITORS OF ROTAMASE ENZYME ACTIVITY |
| 摘要 |
This invention relates to neurotrophic N-glyoxyl-prolyl ester compounds havi ng an affinity for FKBP-type immunophilins, their preparation and use as inhibitors of the enzyme activity associated with Immunophillin proteins, and particularly inhibitors of peptidyl-prolyl isomerase or rotamase enzyme activity.
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| 申请公布号 |
CA2352900(A1) |
申请公布日期 |
1996.12.19 |
| 申请号 |
CA19962352900 |
申请日期 |
1996.06.05 |
| 申请人 |
GPI NIL HOLDINGS, INC. |
发明人 |
STEINER, JOSEPH P.;HAMILTON, GREGORY S. |
| 分类号 |
A61K31/401;A61K31/4025;A61K31/427;A61K31/4439;A61K38/05;A61P25/00;C07D207/16;C07D401/06;C07D405/06;C07D405/12;C07D409/12;C07D409/14;C07D417/12;C07K5/078;(IPC1-7):C07D417/12;A61K31/402;A61K31/443 |
主分类号 |
A61K31/401 |
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