发明名称 |
Dihydropyridine NPY antagonists: piperidine derivatives |
摘要 |
A series of non-peptidergic antagonists of NPY have been synthesized and are comprised of piperidine and tetrahydropyridine derivatives of 4-phenyl-1,4-dihydropyridines of Formula I. <CHEM> As antagonists of NPY-induced feeding behavior, these compounds are expected to act as effective anorexiant agents in promoting weight loss and treating eating disorders. |
申请公布号 |
AU5475896(A) |
申请公布日期 |
1996.12.19 |
申请号 |
AU19960054758 |
申请日期 |
1996.06.06 |
申请人 |
BRISTOL-MYERS SQUIBB COMPANY |
发明人 |
GRAHAM S. POINDEXTER;MARC BRUCE;GRAHAM JOHNSON;KAREN LEBOULLUEC;CHARLES P. SLOAN |
分类号 |
A61K31/445;A61K31/451;A61K31/455;A61P3/04;A61P9/12;A61P25/20;A61P25/24;A61P25/26;A61P43/00;C07D211/90;C07D413/12;C07D413/14 |
主分类号 |
A61K31/445 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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