| 摘要 |
<p>Synthetic peptides having at least fourteen amino acid residues each including two linked amino acid sequences which correspond to positions p200-208 and p262-266 of the human acetylcholine receptor α-subunit, but differing therefrom by one or more amino acid substitutions in each of said positions, are disclosed. These peptides inhibit the proliferative response of human peripheral blood lymphocytes to the myasthenogenic peptides p195-212 and p259-271 and are suitable for treatment of subjects afflicted with myasthenia gravis.</p> |
