发明名称 |
METHOD AND COMPOSITIONS FOR INHIBITION OF ADAPTOR PROTEIN/TYROSINE KINASE INTERACTIONS |
摘要 |
The present invention relates to methods and compositions for the inhibition of adaptor protein/protein tyrosine kinase protein interactions, especially wherein those interactions involving a protein tyrosine kinase capable of complexing with a member of the SH2-and/or SH3-containing family of adaptor proteins are associated with a cell proliferative disorder. Specifically, the present invention relates to particular compounds, especially quinazoline derivative compounds, and methods utilizing such compounds.
|
申请公布号 |
WO9640115(A1) |
申请公布日期 |
1996.12.19 |
申请号 |
WO1996US08741 |
申请日期 |
1996.06.05 |
申请人 |
SUGEN, INC. |
发明人 |
TANG, PENG, CHO;MCMAHON, GERALD;HARRIS, G., DAVIS |
分类号 |
A61K31/40;A61K31/403;A61K31/404;A61P35/00;C07D209/08;C07D209/14;(IPC1-7):A61K31/40;C07D403/10 |
主分类号 |
A61K31/40 |
代理机构 |
|
代理人 |
|
主权项 |
|
地址 |
|