| 发明名称 |
Process for converting loracarbef dihydrate to loracarbef monohydrate |
| 摘要 |
<p>A process for the preparation of the crystalline monohydrate form of the compound of formula (I) <CHEM> which includes exposing the crystalline dihydrate form of the compound of formula (I) to a temperature of between about 50 DEG and 65 DEG C and a relative humidity of between about 60 to about 100%.</p> |
| 申请公布号 |
EP0627430(B1) |
申请公布日期 |
1996.12.18 |
| 申请号 |
EP19940303945 |
申请日期 |
1994.06.01 |
| 申请人 |
ELI LILLY AND COMPANY |
发明人 |
PLOCHARCZYK, EDWARD FRANCIS;STROUSE, ERIN ECKERT |
| 分类号 |
A61K31/435;A61P31/00;A61P31/04;C07D463/00;C07D463/22;(IPC1-7):C07D463/00 |
主分类号 |
A61K31/435 |
| 代理机构 |
|
代理人 |
|
| 主权项 |
|
| 地址 |
|
