摘要 |
PURPOSE: To obtain a new steroid derivative useful for medicines having an antitumor action, etc. CONSTITUTION: A compound of formula I (R is a 1-4C alkyl; X, Y are hydroxyl group, a group capable of being easily hydrolyzed to form the hydroxyl group). For example, a compound of formula II. The compound of formula I is obtained by producing an allyl alcohol compound of formula IV from 3β,12β-dihydroxy-5α- pregnan-20-one of formula III as a starting raw material and subsequently reacting the compound of formula IV with m-chloroperbenzoic acid in the presence of a base such as sodium bicarbonate.
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